组装效率高

• You L, Omollo E O, Yu C, et al. Structural basis for intrinsic transcription termination[J]. Nature, 2023.(IF 64.80)

• Huang J, Yang L, Yang L, et al. Stigma receptors control intraspecies and interspecies barriers in Brassicaceae[J]. Nature, 2023.(IF 64.80)

• Shi Y J, Ding Z Y, Wu Y, et al. Quadruple pegRNA enables programmable and efficient large genomic insertion[J]. Nature, 2026.(IF 48.50)

• An Bolin, Tang Tzu-Chieh, Zhang Q, et al. Synthetic circuits for cell ratio control Bolin[J]. Nature, 2026.(IF 48.50)

• Zhang R, He Z, Shi Y, et al. Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale[J]. Cell, 2024.(IF 45.60)

• Wang S Y, Su Y N, Xu Z Q, et al. Discovery and heterologous reconstitution of a plant noncanonical quasi-circadian gene regulatory network[J]. Cell, 2026.(IF 42.50)

• Ge C, Jiang S, Dong X, et al. Engineered living glues secrete therapeutic proteins for treatment of inflammatory bowel disease[J]. Nature Biotechnology.(IF 41.70)

• Jiang L, Xie X, Su N, et al. Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells[J]. Nature Methods, 2023.(IF 36.10)

• Lei X, Huang A, Chen D, et al. Rapid generation of long, chemically modified pegRNAs for prime editing[J]. Nature Biotechnology, 2024.(IF 33.10)

• Liu R, Yang J, Yao J, et al. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins[J]. Nature biotechnology, 2022.(IF 33.10)

• Zhang Y, Dai F, Chen N, et al. Structural insights into VAChT neurotransmitter recognition and inhibition[J]. Cell Research, 2024.(IF 28.10)

• Zou Z P, Du Y, Fang T T, et al. Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice[J]. Cell Host & Microbe, 2022.(IF 20.60)

• Xun D, Liu Y, Cui M, et al. Hierarchical amyloid-DNA complex encoding multi-scale embedded information security[J]. Matter, 2026.(IF 17.50)

• Jiang C, Yu C, Sun S, et al. A new anti-CRISPR gene promotes the spread of drug-resistance plasmids in Klebsiella pneumoniae[J]. Nucleic Acids Research, 2024.(IF 16.60)

• Wang T, Zou J, Wang K, et al. Chemoenzymatic Synthesis of the Cyclopiane Family of Diterpenoid Natural Products[J]. Angewandte Chemie International Edition, 2025.(IF 16.10)

• Ye D, Shao Y, Li W R, et al. Characterization and Engineering of Two Highly Paralogous Sesquiterpene Synthases Reveal a Regioselective Reprotonation Switch[J]. Angewandte Chemie International Edition, 2024.(IF 16.10)

• Liu X, Wang Y, Yang P, et al. Dynamic recruitment of CaMKII into SHANK3 phase-separated condensates tunes postsynaptic density remodeling during long-term potentiation[J]. Nature Communications, 2026.(IF 15.70)

• Wang N, Hou F, Ma S, et al. Targeted stress granule regulation by engineering a non-catalytic O-GlcNAc transferase[J]. Nature Communications, 2026.(IF 15.70)

• Wan W, Dong H, Lai D H, et al. The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments[J]. Nature communications, 2023.(IF 14.70)

• Chen D, Song Z, Han J, et al. Targeted Discovery of Glycosylated Natural Products by Tailoring Enzyme-Guided Genome Mining and MS-Based Metabolome Analysis[J]. Journal of the American Chemical Society, 2024.(IF 14.40)

• Liu R, Yao J, Zhou S, et al. Spatiotemporal control of RNA metabolism and CRISPR–Cas functions using engineered photoswitchable RNA-binding proteins[J]. Nature Protocols, 2023.(IF 13.10)

• Bai X, Sun P, Wang X, et al. Structure and dynamics of the EGFR/HER2 heterodimer[J]. Cell Discovery, 2023.(IF 13.00)

• Zuo F, Jiang L, Su N, et al. Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA[J]. Nature Chemical Biology, 2024.(IF 12.90)

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