产品详情介绍
DNase I，即Deoxyribonuclease I，中文名称为脱氧核糖核酸酶I，是一种可以消化单链或双链DNA产生单脱氧核苷酸或单链或双链的寡脱氧核苷酸的核酸内切酶。DNase I水解单链或双链DNA后的产物，5'端为磷酸基团，3'端为羟基。DNase I活性依赖于钙离子，并能被镁离子或二价锰离子激活。镁离子存在条件下，DNase I可随机剪切双链DNA的任意位点；二价锰离子存在条件下，DNase I可在同一位点剪切DNA双链，形成平末端，或1-2个核苷酸突出的粘末端。
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Hu L, Lu W, Huang Z, et al. SNORA11B recruits SWI/SNF to suppress esophageal squamous cell carcinoma malignancy by promoting GPD1-mediated G3P accumulation and mitochondrial damage[J]. Oncogene, 2026.(IF 9.10)
Sun W, Wang J, Liu W, et al. Histone marks enable formation of immiscible phase-separated chromatin compartments[J]. Cell Reports, 2025.(IF 6.90)
Yang J, Yang Y, Zhang X, et al. HDAC2-mediated recruitment of METTL3 to chromatin regulates human embryonic stem cell differentiation[J]. Cell Reports, 2025.(IF 6.90)
Zhai T, Teng J, Gu M, et al. Genome-wide identification and expression analysis of the Nitrile-specifier proteins (NSPs) in Brassica napus[J]. Current Plant Biology, 2024.(IF 5.40)
